Jonas C. Schupp is a physician-scientist and Clinician-Scientist Professor (funded by the Else Kröner-Fresenius-Stiftung) at Hannover Medical School (MHH), where he heads the Center for Interstitial Lung Diseases. He is a Principal Investigator within the BREATH site of the German Center for Lung Research (DZL). He also holds an appointment as Adjunct Assistant Professor at Yale School of Medicine, reflecting a long-standing transatlantic research collaboration.
His work sits at the intersection of clinical medicine, molecular biology, and translational research. Clinically and scientifically, he specializes in interstitial lung diseases—including sarcoidosis, idiopathic pulmonary fibrosis (IPF), pleuroparenchymal fibroelastosis (PPFE), and connective tissue disease-associated ILD. His research program applies single-cell and spatial transcriptomics, multi-omics, and advanced translational approaches to define the cellular and molecular drivers of sarcoidosis and pulmonary fibrosis, with particular interest in aberrant epithelial cell states, cellular senescence and biological aging, and the spatial architecture of fibrotic tissue.
Prof. Schupp trained as a clinician-scientist through the PRACTIS program at MHH and developed his research profile in close collaboration with colleagues at Yale, contributing to foundational single-cell studies of the fibrotic lung. He combines this molecular expertise with a strong grounding in clinical trial methodology and regulatory science, and is an active contributor to grant-funded translational initiatives, multi-center consortia, and the training of the next generation of clinician-scientists. He is a Fellow of the American Thoracic Society (ATSF).
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